Label-free detection techniques for protein microarrays: Prospects, merits and challenges
نویسندگان
چکیده
منابع مشابه
Label-free detection techniques for protein microarrays: prospects, merits and challenges.
Protein microarrays, on which thousands of discrete proteins are printed, provide a valuable platform for functional analysis of the proteome. They have been widely used for biomarker discovery and to study protein-protein interactions. The accomplishments of DNA microarray technology, which had enabled massive parallel studies of gene expression, sparked great interest for the development of p...
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Protein microarray technology has gone through numerous innovative developments in recent decades. In this review, we focus on the development of protein detection methods embedded in the technology. Early microarrays utilized useful chromophores and versatile biochemical techniques dominated by high-throughput illumination. Recently, the realization of label-free techniques has been greatly ad...
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ژورنال
عنوان ژورنال: PROTEOMICS
سال: 2009
ISSN: 1615-9853
DOI: 10.1002/pmic.200900458